BDBM279516 3-methyl-1-(5-(pyridin-4-yl)-1H-benzo[d]imidazol-2-yl)-N-(2,2,2-trifluoroethyl)butan-1-amine::US10035777, Example 66

SMILES CC(C)C[C@@H](NCC(F)(F)F)c1nc2cc(ccc2[nH]1)-c1ccncc1

InChI Key InChIKey=INZSNRIGUQZMQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 279516   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM279516(US10035777, Example 66 | 3-methyl-1-(5-(pyridin-4-...)
Affinity DataIC50: 45nMpH: 7.4 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent