BDBM28014 2-[(2H-1,3-benzodioxol-5-ylmethyl)amino]-N-[1-(4-chlorophenyl)propan-2-yl]-4-(2,6-dimethoxypyridin-3-yl)pyrimidine-5-carboxamide::trisubstituted pyrimidine analogue, 11o

SMILES COc1ccc(c(OC)n1)-c1nc(NCc2ccc3OCOc3c2)ncc1C(=O)NC(C)Cc1ccc(Cl)cc1

InChI Key InChIKey=XKLYEDFEHKNGKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28014   

TargetExtracellular calcium-sensing receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM28014(2-[(2H-1,3-benzodioxol-5-ylmethyl)amino]-N-[1-(4-c...)
Affinity DataIC50: 150nMAssay Description:Antagonist activity of test compounds was measured in HEK293 cells stably expressing the human recombinant CaR (HEK-CaR) by determining the ability o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed