BDBM280374 US10030012, Example 4::ethyl 4-[4-(1H- pyrazol-1- yl)piperidin- 1yl]azepane-1- carboxylate

SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)n1cccn1

InChI Key InChIKey=DSXCSLGHRFQRAF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280374   

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280374(ethyl 4-[4-(1H- pyrazol-1- yl)piperidin- 1yl]azepa...)
Affinity DataEC50:  140nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
US Patent