BDBM280392 US10030012, Example 22::ethyl 4-(4-{5- [1-(propan-2-yl)- 1H-pyrazol-4-yl]- 1H-pyrazol-1- yl}piperidin-1- yl)azepane-1- carboxylate

SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)n1nccc1-c1cnn(c1)C(C)C

InChI Key InChIKey=UIQZIQYVUQWSPJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 280392   

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280392(ethyl 4-(4-{5- [1-(propan-2-yl)- 1H-pyrazol-4-yl]-...)
Affinity DataEC50:  200nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280392(ethyl 4-(4-{5- [1-(propan-2-yl)- 1H-pyrazol-4-yl]-...)
Affinity DataEC50:  680nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
US Patent