BDBM28073 (4Z)-6-(1H-indol-5-ylamino)-4-({[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-1,2,3,4-tetrahydroisoquinoline-1,3-dione::isoquinolinedione, 28

SMILES O=C1NC(=O)c2ccc(Nc3ccc4[nH]ccc4c3)cc2C1=CNc1ccc(CN2CCCCC2)cc1

InChI Key InChIKey=MTWRGQNBACFUJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28073   

TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28073((4Z)-6-(1H-indol-5-ylamino)-4-({[4-(piperidin-1-yl...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed