BDBM28081 (4Z)-4-[({4-[(dimethylamino)methyl]phenyl}amino)methylidene]-6-[(3-methoxyphenyl)amino]-1,2,3,4-tetrahydroisoquinoline-1,3-dione::isoquinolinedione, 36

SMILES COc1cccc(Nc2ccc3C(=O)NC(=O)C(=CNc4ccc(CN(C)C)cc4)c3c2)c1

InChI Key InChIKey=LIYQZXZFOLJIIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28081   

TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28081((4Z)-4-[({4-[(dimethylamino)methyl]phenyl}amino)me...)
Affinity DataIC50: 1.39E+3nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed