BDBM28083 (4Z)-4-[({4-[(dimethylamino)methyl]phenyl}amino)methylidene]-6-[(3-acetylphenyl)amino]-1,2,3,4-tetrahydroisoquinoline-1,3-dione::isoquinolinedione, 38

SMILES CN(C)Cc1ccc(NC=C2C(=O)NC(=O)c3ccc(Nc4cccc(c4)C(C)=O)cc23)cc1

InChI Key InChIKey=NKQUSYWUVWJWRR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28083   

TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28083((4Z)-4-[({4-[(dimethylamino)methyl]phenyl}amino)me...)
Affinity DataIC50: 887nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed