BDBM28093 3-cyanoquinoline, 18::7-{[3-(dimethylamino)propyl]amino}-6-methoxy-4-({4-[(1,4,5-trimethyl-1H-imidazol-2-yl)sulfanyl]phenyl}amino)quinoline-3-carbonitrile

SMILES COc1cc2c(Nc3ccc(Sc4nc(C)c(C)n4C)cc3)c(cnc2cc1NCCCN(C)C)C#N

InChI Key InChIKey=NMAHGTNXQATLSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28093   

TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28093(7-{[3-(dimethylamino)propyl]amino}-6-methoxy-4-({4...)
Affinity DataIC50: 394nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed