BDBM281113 US10022354, Example 53

SMILES CNC(=O)c1cc(C)nc(C2CCN(C(=O)c3cc(C(C)C)n[nH]3)C2)c1

InChI Key InChIKey=IQPYVZCXHBQCHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 281113   

TargetLysine-specific demethylase 5A(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 281113BDBM281113(US10022354, Example 53)
Affinity DataIC50: 4.20nMpH: 7.0 T: 2°CAssay Description:Full length KDM5A enzyme was expressed and purified inhouse. Biotin-H3K4me3 peptide was purchased from New England Biolabs. HTRF reagents (containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2018
Entry Details
US Patent