BDBM281209 US10022354, Example 149

SMILES CC(C)c1cc(C(=O)N2CCC(NC(=O)c3ccncc3)C2)[nH]n1

InChI Key InChIKey=LONIOBYLWBYSPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 281209   

TargetLysine-specific demethylase 5A(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 281209BDBM281209(US10022354, Example 149)
Affinity DataIC50: 2.5nMpH: 7.0 T: 2°CAssay Description:Full length KDM5A enzyme was expressed and purified inhouse. Biotin-H3K4me3 peptide was purchased from New England Biolabs. HTRF reagents (containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2018
Entry Details
US Patent