BDBM28228 7-{5-[(3,4-dimethoxyphenyl)methyl]-4H-1,2,4-triazol-3-yl}-1,6-naphthyridin-8-ol::triazole substituted naphthyridine, 12f

SMILES COc1ccc(Cc2nnc([nH]2)-c2ncc3cccnc3c2O)cc1OC

InChI Key InChIKey=RIIRQZDHOJXXCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28228   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28228(7-{5-[(3,4-dimethoxyphenyl)methyl]-4H-1,2,4-triazo...)
Affinity DataIC50: 6.30E+3nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2009
Entry Details Article
PubMed