BDBM283312 4-[2-(4-aminopiperidin-1-yl)-1- methyl-5-[4-(methylamino)phenyl]- 6-oxopyrimidin-4-yl]-2- fluorobenzonitrile::US10023543, Example 90

SMILES CNc1ccc(cc1)-c1c(nc(N2CCC(N)CC2)n(C)c1=O)-c1ccc([N+]#[C-])c(F)c1

InChI Key InChIKey=MNGAGWVKGZQYRN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 283312   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM283312(US10023543, Example 90 | 4-[2-(4-aminopiperidin-1-...)
Affinity DataIC50: 100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2019
Entry Details
US Patent