BDBM283319 4-[2-(4-aminopiperidin-1-yl)-5-[4-(2- hydroxyethoxy)phenyl]-1-methyl-6- oxopyrimidin-4-yl]-2- fluorobenzonitrile::US10023543, Example 96::US9573930, Example 96

SMILES Cn1c(nc(-c2ccc([N+]#[C-])c(F)c2)c(-c2ccc(OCCO)cc2)c1=O)N1CCC(N)CC1

InChI Key InChIKey=GHWRPIYAKKDPKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 283319   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM283319(US9573930, Example 96 | US10023543, Example 96 | 4...)
Affinity DataIC50: 100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM283319(US9573930, Example 96 | US10023543, Example 96 | 4...)
Affinity DataIC50: 100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent