BDBM283387 N-((6-amino-2-methylpyridin-3-yl)methyl)-2- ((3-chloroquinolin-6-yl)methyl)isonicotinamide::US10023557, Example 39

SMILES Cc1nc(N)ccc1CNC(=O)c1ccnc(CC2=CC3C=C(Cl)C=NC3C=C2)c1

InChI Key InChIKey=NIYJHTYTWUQRKB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 283387   

TargetPlasma kallikrein(Human)
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283387(US10023557, Example 39 | N-((6-amino-2-methylpyrid...)
Affinity DataIC50: 100nMpH: 7.5Assay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2019
Entry Details
US Patent