BDBM28366 N-[4-(2-cyanoethyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide::cyclohexyl benzamide derivative, 5

SMILES C[C@](O)(c1ccc(cc1)C(=O)N(C1CC1)[C@@H]1CC[C@H](CCC#N)CC1)C(F)(F)F

InChI Key InChIKey=IHSUMNRQVFTRRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28366   

LigandPNGBDBM28366(N-[4-(2-cyanoethyl)cyclohexyl]-N-cyclopropyl-4-[(2...)
Affinity DataIC50: 2.80nMpH: 7.5 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed