BDBM28409 (2E)-3-{3-[6-(morpholin-4-yl)pyrazin-2-yl]phenyl}prop-2-enoic acid::pyrazine inhibitor, 12

SMILES OC(=O)\C=C\c1cccc(c1)-c1cncc(n1)N1CCOCC1

InChI Key InChIKey=YFZGNPRWWXZIMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28409   

TargetSerine/threonine-protein kinase pim-2(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM28409((2E)-3-{3-[6-(morpholin-4-yl)pyrazin-2-yl]phenyl}p...)
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed