BDBM28418 (2E)-3-(3-{6-[(4-aminocyclohexyl)amino]pyrazin-2-yl}phenyl)prop-2-enoic acid::pyrazine inhibitor, 24

SMILES N[C@H]1CC[C@H](CC1)Nc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1

InChI Key InChIKey=GPICQYUBSFLTRN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28418   

TargetSerine/threonine-protein kinase pim-2(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM28418((2E)-3-(3-{6-[(4-aminocyclohexyl)amino]pyrazin-2-y...)
Affinity DataIC50: 19nMAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed