BDBM28471 (2S)-3-methyl-2-({12-[(propoxycarbonyl)amino]-8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-5-}sulfonamido)butanoic acid::dibenzofuran (DBF) scaffold, (S)-16

SMILES CCCOC(=O)Nc1ccc2oc3cc(ccc3c2c1)S(=O)(=O)N[C@@H](C(C)C)C(O)=O

InChI Key InChIKey=WDMMHRSZAREYDM-IBGZPJMESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28471   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28471((2S)-3-methyl-2-({12-[(propoxycarbonyl)amino]-8-ox...)
Affinity DataIC50:  10nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28471((2S)-3-methyl-2-({12-[(propoxycarbonyl)amino]-8-ox...)
Affinity DataIC50:  5.60nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed