BDBM28479 (2S)-2-({12-[(cyclopentylcarbamoyl)amino]-8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-5-}sulfonamido)-3-methylbutanoic acid::dibenzofuran (DBF) scaffold, (S)-24

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(NC(=O)NC3CCCC3)cc21)C(O)=O

InChI Key InChIKey=LDOSBGUASYKJNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28479   

TargetCollagenase 3(Human)
Wyeth Research

LigandPNGBDBM28479((2S)-2-({12-[(cyclopentylcarbamoyl)amino]-8-oxatri...)
Affinity DataIC50: 2.10nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

LigandPNGBDBM28479((2S)-2-({12-[(cyclopentylcarbamoyl)amino]-8-oxatri...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed