BDBM284818 4-(5-(4-amino-5-(1-isopropyl-1H-1,2,3-triazol-5-yl)pyrrolo[2,1-f] [1,2,4]triazin-7-yl)pyridin-3-yl)thiomorpholine 1,1-dioxide::US10023576, Example 8

SMILES CC(C)n1nncc1-c1cc(-c2cncc(c2)N2CCS(=O)(=O)CC2)n2ncnc(N)c12

InChI Key InChIKey=BCZSTMHCRPXXKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284818   

LigandPNGBDBM284818(US10023576, Example 8 | 4-(5-(4-amino-5-(1-isoprop...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent