BDBM284840 7-(1-(tetrahydro-2H-pyran-4-yl)-1H-benzo[d]imidazol-6-yl)-5-(1- (tetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-yl)pyrrolo[2,1-f][1,2,4] triazin-4-amine::US10023576, Example 30

SMILES Nc1ncnn2c(cc(-c3ccnn3C3CCOCC3)c12)-c1ccc2ncn(C3CCOCC3)c2c1

InChI Key InChIKey=UCZCIGKJJZVCOD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284840   

LigandPNGBDBM284840(US10023576, Example 30 | 7-(1-(tetrahydro-2H-pyran...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
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Date in BDB:
1/11/2019
Entry Details
US Patent