BDBM284846 4-(6-(4-amino-5-(1-(tetrahydro-2H-pyran-4-yl)-1H-1,2,3- triazol-5-yl)pyrrolo[2,1-f][1,2,4]triazin-7-yl)-4-fluoro-1H- indazol-1-yl)tetrahydro-2H-thiopyran 1,1-dioxide::US10023576, Example 36

SMILES Nc1ncnn2c(cc(-c3cnnn3C3CCOCC3)c12)-c1cc(F)c2cnn(C3CCS(=O)(=O)CC3)c2c1

InChI Key InChIKey=LMIFCHWLXADGJG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284846   

LigandPNGBDBM284846(US10023576, Example 36 | 4-(6-(4-amino-5-(1-(tetra...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent