BDBM284855 7-(1-(cyclopropylmethyl)-1H-benzo[d]imidazol-6-yl)-5-(1- (tetrahydro-2H-pyran-4-yl)-1H-1,2,3-triazol-5-yl)pyrrolo[2,1-f] [1,2,4]triazin-4-amine::US10023576, Example 45

SMILES Nc1ncnn2c(cc(-c3cnnn3C3CCOCC3)c12)-c1ccc2ncn(CC3CC3)c2c1

InChI Key InChIKey=QIMBERJOJIPVLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284855   

LigandPNGBDBM284855(US10023576, Example 45 | 7-(1-(cyclopropylmethyl)-...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent