BDBM284890 2-(6-(4-amino-5-(1-(tetrahydro-2H- pyran-4-yl)-1H-1,2,3-triazol-5- yl)pyrrolo[2,1-f][1,2,4]triazin-7-yl)-1H- benzo[d]imidazol-1-yl)benzamide::US10023576, Example 81

SMILES NC(=O)c1ccccc1-n1ncc2ccc(cc12)-c1cc(-c2cnnn2C2CCOCC2)c2c(N)ncnn12

InChI Key InChIKey=IIKBBVFHGMKRHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284890   

LigandPNGBDBM284890(US10023576, Example 81 | 2-(6-(4-amino-5-(1-(tetra...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent