BDBM284895 1-(5-(4-amino-5-chloropyrrolo[2,1-f] [1,2,4]triazin-7-yl)pyridin-3-yl)-4- (cyclopropanecarbonyl)-3,3- dimethylpiperazin-2-one::US10023576, Example 86

SMILES CC1(C)N(CCN(C1=O)c1cncc(c1)-c1cc(Cl)c2c(N)ncnn12)C(=O)C1CC1

InChI Key InChIKey=IGFMZNNIIBTDSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284895   

LigandPNGBDBM284895(US10023576, Example 86 | 1-(5-(4-amino-5-chloropyr...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent