BDBM284897 4-acetyl-1-(5-(4-amino-5- (trifluoromethyl)pyrrolo[2,1-f][1,2,4] triazin-7-yl)pyridin-3-yl)-3,3- dimethylpiperazin-2-one::US10023576, Example 88

SMILES CC(=O)N1CCN(C(=O)C1(C)C)c1cncc(c1)-c1cc(c2c(N)ncnn12)C(F)(F)F

InChI Key InChIKey=CCZIWCGQZNVOEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284897   

LigandPNGBDBM284897(US10023576, Example 88 | 4-acetyl-1-(5-(4-amino-5-...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
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Date in BDB:
1/11/2019
Entry Details
US Patent