BDBM284918 (S)-4-acetyl-1-(6-(4-amino-5-(1- methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f] [1,2,4]triazin-7-yl)pyridin-2-yl)-3,3,6- trimethylpiperazin-2-one::US10023576, Example 110

SMILES C[C@H]1CN(C(C)=O)C(C)(C)C(=O)N1c1cccc(n1)-c1cc(-c2cnn(C)c2)c2c(N)ncnn12

InChI Key InChIKey=YBPUTSRHQGKNFQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284918   

LigandPNGBDBM284918(US10023576, Example 110 | (S)-4-acetyl-1-(6-(4-ami...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent