BDBM285005 N-[4-chloro-3-(6-fluoro-2-methyl-1- oxoisoquinolin-4-yl)phenyl]ethanesulfonamide::US10023592, Example 50::US10941160, Example 50

SMILES CCS(=O)(=O)Nc1ccc(Cl)c(c1)-c1cn(C)c(=O)c2ccc(F)cc12

InChI Key InChIKey=XPSHISSYDMXRNH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285005   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285005(US10023592, Example 50 | N-[4-chloro-3-(6-fluoro-2...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285005(US10023592, Example 50 | N-[4-chloro-3-(6-fluoro-2...)
Affinity DataIC50: 500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent