BDBM28506 (3R,5S)-5-[2-(4-{[1-(thiophene-2-sulfonyl)-1H-indol-5-yl]amino}thieno[3,2-d]pyrimidin-6-yl)ethynyl]pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15r

SMILES O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc4n(ccc4c3)S(=O)(=O)c3cccs3)c2s1)N1CCOCC1

InChI Key InChIKey=ZFBVZPNEZMXKOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28506   

LigandPNGBDBM28506((3R,5S)-5-[2-(4-{[1-(thiophene-2-sulfonyl)-1H-indo...)
Affinity DataIC50: 120nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28506((3R,5S)-5-[2-(4-{[1-(thiophene-2-sulfonyl)-1H-indo...)
Affinity DataIC50: 150nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed