BDBM285355 5-[2-(cyclopropylmethoxy)-5- ethylsulfonylphenyl]-1-methyl-3- (methylamino)pyridin-2-one::US10023592, Example 409

SMILES CCS(=O)(=O)c1ccc(OCC2CC2)c(c1)-c1cc(NC)c(=O)n(C)c1

InChI Key InChIKey=DFUQKHKWPVSPHV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285355   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285355(US10023592, Example 409 | 5-[2-(cyclopropylmethoxy...)
Affinity DataIC50: 500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent