BDBM285364 3-chloro-1-methyl-5-[5- (methylsulfonylmethyl)-2-(2,2,2- trifluoroethoxy)phenyl]pyridin-2-one::US10023592, Example 418

SMILES Cn1cc(cc(Cl)c1=O)-c1cc(CS(C)(=O)=O)ccc1OCC(F)(F)F

InChI Key InChIKey=NVJHSZWCYGYFIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285364   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285364(US10023592, Example 418 | 3-chloro-1-methyl-5-[5- ...)
Affinity DataIC50: 500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent