BDBM285376 N-[3-(1,5-dimethyl-6-oxopyridin-3-yl)-4- (trans-4-hydroxycyclohexyl)oxyphenyl] ethanesulfonamide::US10023592, Example 430::US10941160, Example 430

SMILES CCS(=O)(=O)Nc1ccc(O[C@H]2CC[C@H](O)CC2)c(c1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=MYRKCCRWKSPYFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285376   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285376(US10023592, Example 430 | N-[3-(1,5-dimethyl-6-oxo...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285376(US10023592, Example 430 | N-[3-(1,5-dimethyl-6-oxo...)
Affinity DataIC50: 500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent