BDBM285385 N-[3-(1,5-dimethyl-6-oxopyridin-3-yl)-4- (oxan-4-yloxy)phenyl]methanesulfonamide::US10023592, Example 439

SMILES Cc1cc(cn(C)c1=O)-c1cc(NS(C)(=O)=O)ccc1OC1CCOCC1

InChI Key InChIKey=HRMPOYZNAUWFGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285385   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285385(US10023592, Example 439 | N-[3-(1,5-dimethyl-6-oxo...)
Affinity DataIC50: 500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent