BDBM285411 5-[2-(cyclopropylmethylamino)-5- ethylsulfonylphenyl]-1,3- dimethylpyridin-2-one::US10023592, Example 465

SMILES CCS(=O)(=O)c1ccc(NCC2CC2)c(c1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=GVRPYQUQJXZWGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285411   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285411(US10023592, Example 465 | 5-[2-(cyclopropylmethyla...)
Affinity DataIC50: 500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent