BDBM285414 5-[2-(cyclopropylmethylamino)-5- methylsulfonylphenyl]-1-methylpyridin- 2-one::BDBM486258::US10023592, Example 468

SMILES Cn1cc(ccc1=O)-c1cc(ccc1NCC1CC1)S(C)(=O)=O

InChI Key InChIKey=KUTCBZANVXFTRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285414   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285414(US10023592, Example 468 | BDBM486258 | 5-[2-(cyclo...)
Affinity DataIC50: 500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285414(US10023592, Example 468 | BDBM486258 | 5-[2-(cyclo...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
US Patent