BDBM285415 3-(dimethylamino)-5-(2-ethoxy-5- ethylsulfonylphenyl)-1-methylpyridin-2-one::US10023592, Example 469

SMILES CCOc1ccc(cc1-c1cc(N(C)C)c(=O)n(C)c1)S(=O)(=O)CC

InChI Key InChIKey=HAZMIJIKTRRBFM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285415   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285415(US10023592, Example 469 | 3-(dimethylamino)-5-(2-e...)
Affinity DataIC50: 500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent