BDBM28555 N,12-dimethyl-8-(methylamino)-5-thia-3,7,10,12-tetraazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),3,7,10-pentaene-4-carboxamide::thiazole-based tricyclic inhibitor, 30a

SMILES CNC(=O)c1nc2c(nc(NC)c3ncn(C)c23)s1

InChI Key InChIKey=BYMRVDVGQVMXFP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28555   

LigandPNGBDBM28555(N,12-dimethyl-8-(methylamino)-5-thia-3,7,10,12-tet...)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
LigandPNGBDBM28555(N,12-dimethyl-8-(methylamino)-5-thia-3,7,10,12-tet...)
Affinity DataIC50: 840nMT: 2°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed