BDBM285555 3-(3,5-dichlorophenyl)-N-propylimidazo[1,2-b]pyridazine-2-carboxamide::US10077269, Example 28::US10669279, Example 28::US9598421, Example 28

SMILES CCCNC(=O)c1nc2cccnn2c1-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=GXYHCJBIWBLNEK-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285555   

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 15.6nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 15.6nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 15.6nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 31.7nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 31.7nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 31.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 49nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 49nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 49nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 393nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 393nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285555(US10077269, Example 28 | 3-(3,5-dichlorophenyl)-N-...)
Affinity DataIC50: 393nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent