BDBM285566 3-(1,3-benzoxazol-5-yl)-N-cyclopropylimidazo[1,2-b]pyridazine-2-carboxamide::US10077269, Example 39::US10669279, Example 39::US9598421, Example 39

SMILES O=C(NC1CC1)c1nc2cccnn2c1-c1ccc2ocnc2c1

InChI Key InChIKey=WBVHJGBFCGWOMH-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285566   

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 14.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 14.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 14.8nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 26.5nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 26.5nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 26.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 67.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 67.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 67.8nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 3.82E+3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 3.82E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285566(US10077269, Example 39 | 3-(1,3-benzoxazol-5-yl)-N...)
Affinity DataIC50: 3.82E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent