BDBM285577 US10077269, Example 50::US10669279, Example 50::US9598421, Example 50::azetidin-1-yl[3-(2,3-dihydro-1-benzofuran-5-yl)imidazo[1,2-b]pyridazin-2-yl]methanone

SMILES O=C(N1CCC1)c1nc2cccnn2c1-c1ccc2OCCc2c1

InChI Key InChIKey=HVVGNLROCIOALI-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285577   

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 28.1nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 28.1nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 28.1nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 116nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 116nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 116nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 235nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 235nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 235nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 3.14E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 3.14E+3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285577(US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...)
Affinity DataIC50: 3.14E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent