BDBM285591 US10077269, Example 64::US10669279, Example 64::US9598421, Example 64::azetidin-1-yl[3-(5-chloro-2-methylphenyl)imidazo[1,2-b]pyridazin-2-yl]methanone

SMILES Cc1ccc(Cl)cc1-c1c(nc2cccnn12)C(=O)N1CCC1

InChI Key InChIKey=COVWSPFRFUFHGD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 285591   

LigandPNGBDBM285591(US10077269, Example 64 | azetidin-1-yl[3-(5-chloro...)
Affinity DataIC50: 24.2nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285591(US10077269, Example 64 | azetidin-1-yl[3-(5-chloro...)
Affinity DataIC50: 24.2nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285591(US10077269, Example 64 | azetidin-1-yl[3-(5-chloro...)
Affinity DataIC50: 24.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285591(US10077269, Example 64 | azetidin-1-yl[3-(5-chloro...)
Affinity DataIC50: 844nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285591(US10077269, Example 64 | azetidin-1-yl[3-(5-chloro...)
Affinity DataIC50: 844nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285591(US10077269, Example 64 | azetidin-1-yl[3-(5-chloro...)
Affinity DataIC50: 844nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent