BDBM285616 US10077269, Example 86::US10669279, Example 86::US9598421, Example 86::azetidin-1-yl[3-(2,2-difluoro-1,3-benzodioxol-5-yl)imidazo[1,2-b]pyridazin-2-yl]methanone

SMILES FC1(F)Oc2ccc(cc2O1)-c1c(nc2cccnn12)C(=O)N1CCC1

InChI Key InChIKey=CIMWFDZKHUKERW-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285616   

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 5.83nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 5.83nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 5.83nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 7.72nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 7.72nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 7.72nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 25nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 25nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 179nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 179nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285616(US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...)
Affinity DataIC50: 179nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent