BDBM285626 3-(4-chloro-2,5-difluoro-phenyl)-N-ethylimidazo[1,2-b]pyridazine-2-carboxamide::US10077269, Example 96::US10669279, Example 96::US9598421, Example 96

SMILES CCNC(=O)c1nc2cccnn2c1-c1cc(F)c(Cl)cc1F

InChI Key InChIKey=IMOBPVDSTURWHO-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285626   

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 4.58nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 4.58nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 4.58nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 29.2nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 29.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 29.2nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 33.2nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 33.2nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 33.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 908nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 908nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285626(US10077269, Example 96 | 3-(4-chloro-2,5-difluoro-...)
Affinity DataIC50: 908nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent