BDBM285629 3-(4-cyano-5-fluoro-2-methylphenyl)-N-(propan-2-yl)imidazo[1,2-b]pyridazine-2-carboxamide::US10077269, Example 99::US10669279, Example 99::US9598421, Example 99

SMILES CC(C)NC(=O)c1nc2cccnn2c1-c1cc(F)c(cc1C)C#N

InChI Key InChIKey=LCTMXACJLVAYNA-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285629   

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 19.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 19.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 19.8nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 36.2nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 36.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 36.2nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 138nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 138nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 138nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 1.55E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 1.55E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285629(US10077269, Example 99 | 3-(4-cyano-5-fluoro-2-met...)
Affinity DataIC50: 1.55E+3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent