BDBM286341 4-(7-fluoro-[1,2,4] triazolo[1,5-a]pyridin-2- yl)isoquinoline::US9567333, 20

SMILES Fc1ccn2nc(nc2c1)-c1cncc2ccccc12

InChI Key InChIKey=DNAKOMYCSOUSAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286341   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286341(4-(7-fluoro-[1,2,4] triazolo[1,5-a]pyridin-2- yl)i...)
Affinity DataIC50:  1.08E+3nMAssay Description:CYP11B1 Assays: V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfectio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286341(4-(7-fluoro-[1,2,4] triazolo[1,5-a]pyridin-2- yl)i...)
Affinity DataIC50:  22nMAssay Description:CYP11B1 Assays: V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfectio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent