BDBM286349 US11220518, Ex. No. K7::US11780853, Example K7::US9518060, Example K7

SMILES C[C@@H]1CN([C@@H](C)CN1C)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C

InChI Key InChIKey=CEOVOUHGBMXHLJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286349   

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM286349(US9518060, Example K7 | US11220518, Ex. No. K7 | U...)
Affinity DataKi:  0.165nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

TargetProtein kinase C beta type Isoform 2(Human)
Pfizer

US Patent
LigandPNGBDBM286349(US9518060, Example K7 | US11220518, Ex. No. K7 | U...)
Affinity DataKi:  0.165nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

US Patent
LigandPNGBDBM286349(US9518060, Example K7 | US11220518, Ex. No. K7 | U...)
Affinity DataKi:  0.165nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent