BDBM286846 (S)-1-[8-Chloro-3- (5-chloro-2- ethanesulfonyl- benzyl)-2,4-dioxo- 6-trifluoromethyl- 1,2,3,4-tetrahydro- quinazolin-7- ylmethyl]- pyrrolidine-2- carboxylic acid amide::US9567304, Compound F-121::US9567304, Compound F-122

SMILES CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(CN3CCC[C@H]3C(N)=O)c(cc2c1=O)C(F)(F)F

InChI Key InChIKey=VUJRUTCMFBNLPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286846   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM286846(US9567304, Compound F-122 | (S)-1-[8-Chloro-3- (5-...)
Affinity DataIC50: 21nMT: 2°CAssay Description:DDR1 binding activity was measured using the LanthaScreen(Registered trademark) Eu Kinase Binding Assay (manufactured by Life Technologies Corporatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM286846(US9567304, Compound F-122 | (S)-1-[8-Chloro-3- (5-...)
Affinity DataIC50: 30nMT: 2°CAssay Description:DDR1 binding activity was measured using the LanthaScreen(Registered trademark) Eu Kinase Binding Assay (manufactured by Life Technologies Corporatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent