BDBM287165 US9567339, Example A.1.16

SMILES Cc1c(NC(=O)C=C)cccc1-c1ccc(C(N)=O)c2[nH]c(cc12)-c1ccc(F)nc1

InChI Key InChIKey=GFQXHKLIHCXMKO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287165   

TargetTyrosine-protein kinase BTK [393-659](Human)
Abbvie

US Patent
LigandPNGBDBM287165(US9567339, Example A.1.16)
Affinity DataIC50: 100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent