BDBM287706 US10085984, Example 84

SMILES Clc1ccc2nc(-c3cnnc(c3)C3CC3)n(C3CC3)c2c1

InChI Key InChIKey=OPNXKUHBHMVCJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 287706   

TargetCytochrome P450 11B2, mitochondrial(Human)
Viamet Pharmaceuticals (Bermuda)

US Patent
LigandPNGBDBM287706(US10085984, Example 84)
Affinity DataIC50: 100nMAssay Description:V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Viamet Pharmaceuticals (Bermuda)

US Patent
LigandPNGBDBM287706(US10085984, Example 84)
Affinity DataIC50: 300nMAssay Description:V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent