BDBM28783 US11116760, Example 87

SMILES C[C@@H](N(C)c1cc(F)c(C(=O)N[C@H](Cc2ccc(-c3ccc(C#N)cc3Cl)c3ncccc23)C(=O)O)c(F)c1)C(F)(F)F

InChI Key InChIKey=GJLDQOIJTGQIJG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28783   

TargetIntegrin alpha-4/beta-7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 28783BDBM28783(US11116760, Example 87)
Affinity DataEC50:  15nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent